H3K27 acetylation activated-PDLIM7 promotes castration-resistant prostate cancer progression by inducing O-Glycosylation of YAP1 protein

H3K27 acetylation activated-PDLIM7 promotes castration-resistant prostate cancer progression by inducing O-Glycosylation of YAP1 protein

Castration-resistant prostate cancer (CRPC) is a fatal disease that evolves from prostate cancer due to drug resistance after long-term androgen deprivation therapy. In this study, we aimed to find novel molecular targets for treating CRPC. Through peptidome, we screened out polypeptides dysregulate...

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Bibliographic Details
Main Authors: Qing Liu, Hangsheng Zhou, Yanjuan Wang, Jiandong Gui, Dongjie Yang, Jian Sun, Dongsheng Ge, Sheng Wu, Qin Liu, Lijie Zhu, Yuanyuan Mi
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Translational Oncology
Subjects:
PDLIM7
YAP1
CRPC
O-Glycosylation
Docetaxel resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002164

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http://www.sciencedirect.com/science/article/pii/S1936523323002164

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