Novelty in improvement of CAR T cell-based immunotherapy with the aid of CRISPR system
Introduction: Chimeric Antigen Receptor (CAR) T cells have tremendous potentials for cancer treatment; however, various challenges impede their universal use. These restrictions include the poor function of T cells in tumor microenvironments, the shortage of tumor-specific antigens and, finally, the...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-01-01
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Series: | Hematology, Transfusion and Cell Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923001244 |