Differentially mutated subnetworks discovery
Abstract Problem We study the problem of identifying differentially mutated subnetworks of a large gene–gene interaction network, that is, subnetworks that display a significant difference in mutation frequency in two sets of cancer samples. We formally define the associated computational problem an...
Main Authors: | Morteza Chalabi Hajkarim, Eli Upfal, Fabio Vandin |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-03-01
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Series: | Algorithms for Molecular Biology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13015-019-0146-7 |
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