An efficient green synthesis of UNA-nucleoside-5′-triphosphates: A versatile synthon for RNA modification with broad therapeutic potential

A facile, reliable, and an efficient “one-pot, two-step” method for the gram-scale chemical synthesis of UNA-nucleoside-5′-triphosphate, starting from the commercially available nucleoside-5′-triphosphate is described. The overall reaction involves oxidation of nucleoside-5′-triphosphate using sodiu...

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Bibliographic Details
Main Authors: Muthian Shanmugasundaram, Annamalai Senthilvelan, Anilkumar R. Kore
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623000802