Regulation of the somatotropic axis by MYC-mediated miRNA repression
The transcription factor MYC is overexpressed in many human cancers and has a significant causal role in tumor incidence and progression. In contrast, Myc+/− heterozygous mice, which have decreased MYC expression, exhibit a 10–20% increase in lifespan and a decreased incidence or progression of seve...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2023.1269860/full |