Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel

Evaluation of Delafloxacin against a Burkholderia pseudomallei Efflux Mutant Panel

ABSTRACT In vitro activities of delafloxacin and ciprofloxacin were evaluated against Burkholderia pseudomallei mutants expressing or lacking defined resistance-nodulation-cell division (RND) efflux pumps using CLSI methodology at pHs of 5.8 and 7.2. Delafloxacin MIC values were as much as 8-fold lo...

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Bibliographic Details
Main Authors: Sandra P. McCurdy, Nawarat Somprasong, Herbert P. Schweizer
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
Burkholderia
biothreat
efflux pumps
delafloxacin
fluoroquinolone
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00903-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00903-22

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