Effects of ursodeoxycholic acid on the gut microbiome and colorectal adenoma development

Effects of ursodeoxycholic acid on the gut microbiome and colorectal adenoma development

Abstract It has been previously reported that ursodeoxycholic acid (UDCA), a therapeutic bile acid, reduced risk for advanced colorectal adenoma in men but not women. Interactions between the gut microbiome and fecal bile acid composition as a factor in colorectal cancer neoplasia have been postulat...

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Bibliographic Details
Main Authors: Talima Pearson, J. Gregory Caporaso, Monica Yellowhair, Nicholas A. Bokulich, Megha Padi, Denise J. Roe, Betsy C. Wertheim, Mark Linhart, Jessica A. Martinez, Cherae Bilagody, Heidie Hornstra, David S. Alberts, Peter Lance, Patricia A. Thompson
Format: Article
Language:English
Published: Wiley 2019-02-01
Series:Cancer Medicine
Subjects:
bile acid
colorectal adenoma
colorectal cancer
gut microbiome
Ursodeoxycholic acid
Online Access:https://doi.org/10.1002/cam4.1965

Internet

https://doi.org/10.1002/cam4.1965

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