Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology that affects the CNS. While current therapies are primarily directed against the immune system, the new challenge is to address progressive MS with remyelinating and neuroprotective strategies. Here, we develop a highly r...

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Bibliografski detalji
Glavni autori: Panagiotis Douvaras, Jing Wang, Matthew Zimmer, Stephanie Hanchuk, Melanie A. O’Bara, Saud Sadiq, Fraser J. Sim, James Goldman, Valentina Fossati
Format: Članak
Jezik:English
Izdano: Elsevier 2014-08-01
Serija:Stem Cell Reports
Online pristup:http://www.sciencedirect.com/science/article/pii/S2213671114001982