Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

Multiple sclerosis (MS) is a chronic demyelinating disease of unknown etiology that affects the CNS. While current therapies are primarily directed against the immune system, the new challenge is to address progressive MS with remyelinating and neuroprotective strategies. Here, we develop a highly r...

Full description

Bibliographic Details
Main Authors: Panagiotis Douvaras, Jing Wang, Matthew Zimmer, Stephanie Hanchuk, Melanie A. O’Bara, Saud Sadiq, Fraser J. Sim, James Goldman, Valentina Fossati
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671114001982

Internet

http://www.sciencedirect.com/science/article/pii/S2213671114001982

Similar Items