Renin and prorenin have no direct effect on aldosterone synthesis in the human adrenocortical cell lines H295R and HAC15

Renin and prorenin have no direct effect on aldosterone synthesis in the human adrenocortical cell lines H295R and HAC15

Introduction: Transgenic rats expressing the human (pro)renin receptor (h(P)RR) have elevated plasma aldosterone levels despite unaltered levels, in plasma and adrenal, of renin and angiotensin II. Materials and methods: To investigate whether renin/prorenin–(P)RR interaction underlies these elevate...

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Bibliographic Details
Main Authors: Pieter M Jansen, Johannes Hofland, Anton H van den Meiracker, Frank H de Jong, AH Jan Danser
Format: Article
Language:English
Published: SAGE Publications 2012-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320312438792

Internet

https://doi.org/10.1177/1470320312438792

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