Renin and prorenin have no direct effect on aldosterone synthesis in the human adrenocortical cell lines H295R and HAC15
Introduction: Transgenic rats expressing the human (pro)renin receptor (h(P)RR) have elevated plasma aldosterone levels despite unaltered levels, in plasma and adrenal, of renin and angiotensin II. Materials and methods: To investigate whether renin/prorenin–(P)RR interaction underlies these elevate...
Main Authors: | Pieter M Jansen, Johannes Hofland, Anton H van den Meiracker, Frank H de Jong, AH Jan Danser |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2012-09-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.1177/1470320312438792 |
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