Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects

<p>Abstract</p> <p>Pharmacogenetics enables personalised therapy based on genetic profiling and is increasingly applied in drug discovery. Medicines are developed and used together with pharmacodiagnostic tools to achieve desired drug efficacy and safety margins. Genetic polymorphi...

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Bibliographic Details
Main Authors: Matimba Alice, Del-Favero Jurgen, Van Broeckhoven Christine, Masimirembwa Collen
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Human Genomics
Subjects:
pharmacogenetics
cytochrome P450
N-acetyltransferase
single nucleotide polymorphisms
African populations
Online Access:http://www.humgenomics.com/content/3/2/169

Internet

http://www.humgenomics.com/content/3/2/169

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