Release Behavior of the Pineal Hormone Melatonin from Modified Matrix Tablets Based on Poly(<i>L</i>-Lactic Acid) and Its Derivatives

Release Behavior of the Pineal Hormone Melatonin from Modified Matrix Tablets Based on Poly(<i>L</i>-Lactic Acid) and Its Derivatives

Biodegradable polyesters have been researched intensively over the last two decades because of their biodegradability and superb physical properties. However, the use of linear biodegradable polyesters, for the preparation of drug delivery systems (DDS), is hampered by several limitations. In view o...

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Bibliographic Details
Main Authors: Marilena Vlachou, Georgios-Marios Bolbasis, Anna-Evaggelia Trikali, Chrystalla Protopapa, Angeliki Siamidi, Aikaterini Sakellaropoulou, Evi Christodoulou, Nikolaos D. Bikiaris
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Applied Sciences
Subjects:
melatonin
poly(<i>L</i>-lactic acid) (PLA)
PLA-sorbitol
PLA-glycerol
PLA-pentaerythritol
dissolution
Online Access:https://www.mdpi.com/2076-3417/15/4/2054

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https://www.mdpi.com/2076-3417/15/4/2054

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