Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans

Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans

Abstract Background Accelerated age-associated DNA methylation changes in males may explain the earlier onset of age-related diseases (e.g., cardiovascular disease (CVD)) and thus contribute to sexually dimorphic morbidity and lifespan. However, the details regarding the emergence of this sex-biased...

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Bibliographic Details
Main Authors: Fu-Hui Xiao, Xiao-Qiong Chen, Yong-Han He, Qing-Peng Kong
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Clinical Epigenetics
Subjects:
DNA methylation
Middle-age
Cardiovascular disease
Sexual dimorphism
Lifespan
Online Access:http://link.springer.com/article/10.1186/s13148-018-0573-1

Internet

http://link.springer.com/article/10.1186/s13148-018-0573-1

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