Complement C1q (C1qA, C1qB, and C1qC) May Be a Potential Prognostic Factor and an Index of Tumor Microenvironment Remodeling in Osteosarcoma

Complement C1q (C1qA, C1qB, and C1qC) May Be a Potential Prognostic Factor and an Index of Tumor Microenvironment Remodeling in Osteosarcoma

The tumor microenvironment (TME) has important effects on the tumorigenesis and development of osteosarcoma (OS). However, the dynamic mechanism regulating TME immune and matrix components remains unclear. In this study, we collected quantitative data on the gene expression of 88 OS samples from The...

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Bibliographic Details
Main Authors: Long-hao Chen, Jin-Fu Liu, Yan- Lu, Xin-yu He, Chi- Zhang, Hong-hai Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
C1q (A/B/C)
tumor microenvironment
osteosarcoma
tumor-infiltrating immune cells
CIBERSORT
ESTIMATE
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.642144/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.642144/full

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