Establishing a New Platform to Investigate the Efficacy of Oncolytic Virotherapy in a Human Ex Vivo Peritoneal Carcinomatosis Model

Establishing a New Platform to Investigate the Efficacy of Oncolytic Virotherapy in a Human Ex Vivo Peritoneal Carcinomatosis Model

Oncolytic virotherapy constitutes a promising treatment option for many solid cancers, including peritoneal carcinomatosis (PC), which still represents a terminal stage of many types of tumors. To date, the in vitro efficacy of oncolytic viruses is mostly tested in 2D-cultured tumor cell lines due t...

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Bibliographic Details
Main Authors: Jana Koch, Julia Beil, Susanne Berchtold, Dina Mönch, Annika Maaß, Irina Smirnow, Andrea Schenk, Mary E. Carter, Linus D. Kloker, Tobias Leibold, Philipp Renner, Marc-H. Dahlke, Ulrich M. Lauer
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
peritoneal carcinomatosis
ex vivo peritoneal culture model
virotherapy
oncolytic measles vaccine virus
oncolytic vaccinia virus
Online Access:https://www.mdpi.com/1999-4915/15/2/363

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https://www.mdpi.com/1999-4915/15/2/363

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