Phenylalanine as an effective stabilizer and aggregation inhibitor of Bacillus amyloliquefaciens alpha-amylase

Abstract Aromatic compounds are known anti-amyloid aggregates. Their effect on amorphous aggregates of proteins is, however, less studied. We chose aromatic amino acids Trp, Tyr, and Phe, as well as another known stabilizer (i.e. Arg), as potential compatible solvents to be tested on Bacillus amylol...

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Bibliographic Details
Main Authors: Leila Adibi, Parichehreh Yaghmaei, Parvaneh Maghami, Azadeh Ebrahim-Habibi
Format: Article
Language:English
Published: SpringerOpen 2024-06-01
Series:AMB Express
Subjects:
Online Access:https://doi.org/10.1186/s13568-024-01712-5