LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells.

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells.

LAMTOR2 (p14), a part of the larger LAMTOR/Ragulator complex, plays a crucial role in EGF-dependent activation of p42/44 mitogen-activated protein kinases (MAPK, ERK1/2). In this study, we investigated the role of LAMTOR2 in nerve growth factor (NGF)-mediated neuronal differentiation. Stimulation of...

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Main Authors: Bettina Thauerer, Paul Voegele, Natascha Hermann-Kleiter, Nikolaus Thuille, Mariana E G de Araujo, Martin Offterdinger, Gottfried Baier, Lukas A Huber, Gabriele Baier-Bitterlich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24752675/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24752675/pdf/?tool=EBI

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