Allergic sensitization and exposure to ambient air pollution beginning early in life lead to a COPD-like phenotype in young adult mice

Allergic sensitization and exposure to ambient air pollution beginning early in life lead to a COPD-like phenotype in young adult mice

The perinatal period and early infancy are considered critical periods for lung development. During this period, adversities such as environmental exposures, allergic sensitization, and asthma are believed to impact lung health in adulthood. Therefore, we hypothesized that concomitant exposure to al...

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Bibliographic Details
Main Authors: Natália de Souza Xavier Costa, Aila Mirtes Teles, Jôse Mára de Brito, Thaís de Barros Mendes Lopes, Renata Calciolari Rossi, Fernanda Magalhães Arantes Costa, Beatriz Mangueira Saraiva-Romanholo, Adenir Perini, Tatiane Katsue Furuya, Alexis Germán Murillo Carrasco, Mariana Matera Veras, Paulo Hilário Nascimento Saldiva, Roger Chammas, Thais Mauad
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Air pollution
Particulate matter
Asthma
Allergic sensitization
Alveolarization
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322006613

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http://www.sciencedirect.com/science/article/pii/S0147651322006613

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