Development of direct C-3 difluoromethylation reaction for application in synthesis of quinoline-related drugs

Fluorine holds a prominent position within the realm of drug discovery and development, substantiated by its presence in approximately 25% of drugs approved by the US Food and Drug Administration (FDA). Consequently, the advancement of new fluorination reactions stands as a pivotal area in medicina...

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Bibliographic Details
Main Authors: Thanh Tung Truong, John Nielsen
Format: Article
Language:English
Published: Vietnam Ministry of Science and Technology 2024-03-01
Series:Vietnam Journal of Science, Technology and Engineering
Subjects:
Online Access:https://vietnamscience.vjst.vn/index.php/vjste/article/view/1185