The <i>Drosophila</i> RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set

The <i>Drosophila</i> RNA Helicase Belle (DDX3) Non-Autonomously Suppresses Germline Tumorigenesis Via Regulation of a Specific mRNA Set

DDX3 subfamily DEAD-box RNA helicases are essential developmental regulators of RNA metabolism in eukaryotes. <i>belle</i>, the single <i>DDX3 </i>ortholog<i> </i>in <i>Drosophila,</i> is required for fly viability, fertility, and germline stem cell ma...

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Bibliographic Details
Main Authors: Alexei A. Kotov, Baira K. Godneeva, Oxana M. Olenkina, Vladimir E. Adashev, Mikhail V. Trostnikov, Ludmila V. Olenina
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
ddx3 rna helicase
tumorigenesis
drosophila testes
germline stem cells
cyst cells
translational regulation
clip-seq analysis
Online Access:https://www.mdpi.com/2073-4409/9/3/550

Internet

https://www.mdpi.com/2073-4409/9/3/550

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