Enhancing prognostic power in multiple myeloma using a plasma cell signature derived from single-cell RNA sequencing

Enhancing prognostic power in multiple myeloma using a plasma cell signature derived from single-cell RNA sequencing

Abstract Multiple myeloma (MM) is a heterogenous plasma cell malignancy, for which the established prognostic models exhibit limitations in capturing the full spectrum of outcome variability. Leveraging single-cell RNA-sequencing data, we developed a novel plasma cell gene signature. We evaluated an...

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Bibliographic Details
Main Authors: Jian-rong Li, Shahram Arsang-Jang, Yan Cheng, Fumou Sun, Anita D’Souza, Binod Dhakal, Parameswaran Hari, Quillan Huang, Paul Auer, Yong Li, Raul Urrutia, Fenghuang Zhan, John D. Shaughnessy, Siegfried Janz, Jing Dong, Chao Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-024-01024-8

Internet

https://doi.org/10.1038/s41408-024-01024-8

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