Synthesis of 4-(4-chlorophenyl)thiazole compounds: in silico and in vitro evaluations as leishmanicidal and trypanocidal agents

Abstract Neglected tropical diseases are a diverse group of communicable pathologies that mainly prevail in tropical and subtropical regions. Thus, the objective of this work was to evaluate the biological potential of eight 4-(4-chlorophenyl)thiazole compounds. Tests were carried out in silico to e...

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Bibliographic Details
Main Authors: IRANILDO JOSÉ DA CRUZ FILHO, JAMERSON F. DE OLIVEIRA, ALINE CAROLINE S. SANTOS, VALÉRIA R.A. PEREIRA, MARIA CARMO A. DE LIMA
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2023-05-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000100602&lng=en&tlng=en