Synergistic Effect of Pleuromutilins with Other Antimicrobial Agents against Staphylococcus aureus In Vitro and in an Experimental Galleria mellonella Model

Synergistic Effect of Pleuromutilins with Other Antimicrobial Agents against Staphylococcus aureus In Vitro and in an Experimental Galleria mellonella Model

Invasive infections due to Staphylococcus aureus, including methicillin-resistant S. aureus are prevalent and life-threatening. Combinations of antibiotic therapy have been employed in many clinical settings for improving therapeutic efficacy, reducing side effects of drugs, and development of antib...

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Bibliographic Details
Main Authors: Chun-Liu Dong, Lin-Xiong Li, Ze-Hua Cui, Shu-Wen Chen, Yan Q. Xiong, Jia-Qi Lu, Xiao-Ping Liao, Yuan Gao, Jian Sun, Ya-Hong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Pharmacology
Subjects:
pleuromutilins
other antibiotics
antibiotic combination
Staphylococcus aureus
Galleria mellonella model
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00553/full

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http://journal.frontiersin.org/article/10.3389/fphar.2017.00553/full

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