Genetic evidence implicating circulating lipids and lipid drug targets in pterygium

Genetic evidence implicating circulating lipids and lipid drug targets in pterygium

There is limited knowledge about the impact of circulating lipids and lipid-modifying drugs on pterygium development, with conflicting results reported. Our study aimed to address these questions by applying the Mendelian randomization (MR) approach. A two-step MR model was developed. In the first s...

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Bibliographic Details
Main Authors: Yuchen Cai, Fei Fang, Tianyi Zhou, Wenjun Shi, Xueyao Cai, Yao Fu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Pterygium
Circulating lipids
Low-density lipoprotein cholesterol
HMGCR
Mendelian randomization
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702300418X

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http://www.sciencedirect.com/science/article/pii/S200103702300418X

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