Synthesis and Biological Evaluation of Bicalutamide Analogues for the Potential Treatment of Prostate Cancer
The androgen receptor (AR) is a pivotal target for the treatment of prostate cancer (PC) even when the disease progresses toward androgen-independent or castration-resistant forms. In this study, a series of 15 bicalutamide analogues (sulfide, deshydroxy, sulfone, and <i>O</i>-acetylated...
المؤلفون الرئيسيون: | , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
MDPI AG
2020-12-01
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سلاسل: | Molecules |
الموضوعات: | |
الوصول للمادة أونلاين: | https://www.mdpi.com/1420-3049/26/1/56 |