The cytoplasmic location of chicken mx is not the determining factor for its lack of antiviral activity.

Chicken Mx belongs to the Mx family of interferon-induced dynamin-like GTPases, which in some species possess potent antiviral properties. Conflicting data exist for the antiviral capability of chicken Mx. Reports of anti-influenza activity of alleles encoding an Asn631 polymorphism have not been su...

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Bibliographic Details
Main Authors: Camilla T O Benfield, Jon W Lyall, Laurence S Tiley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2922328?pdf=render