MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53

MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53

Introduction: MDM2 is known as the primary negative regulator of p53, and MDM2 promotes lung cancer fibrosis and lung injury through p53-dependent and p53-independent pathways. However, the mechanism by which MDM2 influences the pathogenesis of asthma is unknown. In this study, we investigated the f...

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Bibliographic Details
Main Authors: Su Wang, Shufen Zhong, Ying Huang, Songling Zhu, Shuangfeng Chen, Ran Wang, Sonam Wangmo, Bo Peng, Houkun Lv, Jichao Yang, Liyan Ma, Zhiyang Ling, Yaguang Zhang, Pengfei Sui, Bing Sun
Format: Article
Language:English
Published: Karger Publishers 2024-08-01
Series:Journal of Innate Immunity
Subjects:
mdm2
p53
apoptosis
alveolar type 2 cells
type 2 lung inflammation
Online Access:https://beta.karger.com/Article/FullText/539824

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https://beta.karger.com/Article/FullText/539824

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