Ivermectin Affects Neutrophil-Induced Inflammation through Inhibition of Hydroxylysine but Stimulation of Cathepsin G and Phenylalanine Secretion

Ivermectin Affects Neutrophil-Induced Inflammation through Inhibition of Hydroxylysine but Stimulation of Cathepsin G and Phenylalanine Secretion

The invasion and integrin-dependent adhesion of neutrophils to lung tissues and their secretion lead to the development of pneumonia in various pulmonary pathologies, including acute respiratory distress syndrome in coronavirus disease. We studied the effect of ivermectin, a possible therapeutic age...

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Bibliographic Details
Main Authors: Svetlana I. Galkina, Ekaterina A. Golenkina, Marina V. Serebryakova, Natalia V. Fedorova, Alexander L. Ksenofontov, Vladimir I. Stadnichuk, Galina F. Sud’ina
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
ivermectin
COVID-19 or coronavirus disease
neutrophil
adhesion
secretion
neutrophilic inflammation
Online Access:https://www.mdpi.com/2227-9059/10/12/3284

Internet

https://www.mdpi.com/2227-9059/10/12/3284

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