Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

Differential Type I Interferon Signaling Is a Master Regulator of Susceptibility to Postinfluenza Bacterial Superinfection

ABSTRACT Bacterial superinfections are a primary cause of death during influenza pandemics and epidemics. Type I interferon (IFN) signaling contributes to increased susceptibility of mice to bacterial superinfection around day 7 post-influenza A virus (IAV) infection. Here we demonstrate that the re...

Full description

Bibliographic Details
Main Authors: Kelly M. Shepardson, Kyle Larson, Rachelle V. Morton, Justin R. Prigge, Edward E. Schmidt, Victor C. Huber, Agnieszka Rynda-Apple
Format: Article
Language:English
Published: American Society for Microbiology 2016-07-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00506-16

Internet

https://journals.asm.org/doi/10.1128/mBio.00506-16

Similar Items