Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input

Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input

Summary: The striatum integrates dopaminergic and glutamatergic inputs to select preferred versus alternative actions. However, the precise mechanisms underlying this process remain unclear. One way to study action selection is to understand how it breaks down in pathological states. Here, we explor...

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Bibliographic Details
Main Authors: Michael B. Ryan, Allison E. Girasole, Andrew J. Flores, Emily L. Twedell, Matthew M. McGregor, Rea Brakaj, Ronald F. Paletzki, Thomas S. Hnasko, Charles R. Gerfen, Alexandra B. Nelson
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472400812X

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http://www.sciencedirect.com/science/article/pii/S221112472400812X

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