Evaluating distinct KRAS subtypes as potential biomarkers for immune checkpoint inhibitor efficacy in lung adenocarcinoma

Evaluating distinct KRAS subtypes as potential biomarkers for immune checkpoint inhibitor efficacy in lung adenocarcinoma

BackgroundDespite the acknowledged predictive value of KRAS in immune checkpoint inhibitor (ICI) responses, the heterogeneous behavior of its mutations in this sphere remains largely unexplored. As of now, no studies have definitively categorized KRAS subtype variations as independent prognostic ind...

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Bibliographic Details
Main Authors: Qi Wang, Zhuoran Tang, Chunyu Li, Xuefei Li, Chunxia Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
KRAS
subtype
immune checkpoint inhibitors (ICIs)
lung adenocarcinoma (LUAD)
tumor immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297588/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1297588/full

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