Cortical structure and the risk for Alzheimer’s disease: a bidirectional Mendelian randomization study

Abstract Progressive loss of neurons in a specific brain area is one of the manifestations of Alzheimer’s disease (AD). Much effort has been devoted to investigating brain atrophy and AD. However, the causal relationship between cortical structure and AD is not clear. We conducted a bidirectional tw...

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Bibliographic Details
Main Authors: Bang-Sheng Wu, Ya-Ru Zhang, Hong-Qi Li, Kevin Kuo, Shi-Dong Chen, Qiang Dong, Yong Liu, Jin-Tai Yu
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01599-x