Study on the regulatory effect of Panax notoginseng saponins combined with bone mesenchymal stem cell transplantation on IRAK1/TRAF6-NF-κB pathway in patients with diabetic cutaneous ulcers

Study on the regulatory effect of Panax notoginseng saponins combined with bone mesenchymal stem cell transplantation on IRAK1/TRAF6-NF-κB pathway in patients with diabetic cutaneous ulcers

Abstract Panax notoginseng saponins (PNSs) have been found as the major active ingredient of Panax notoginseng (Burkill) F.H.Chen (PN) leaves, which has the effect of reducing inflammatory response, facilitating fibroblast proliferation, as well as promoting angiogenesis. This study aimed to investi...

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Bibliographic Details
Main Authors: Yuqing Du, Weijian Chen, Youshan Li, Du Liang, Guobin Liu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Panax notoginseng saponins
Bone marrow mesenchymal stem cells
Diabetic cutaneous ulcer
Bioinformatics
miR-146a-5p
IRAK1/TRAF6-NF-κB signaling pathway
Online Access:https://doi.org/10.1186/s13018-022-03467-w

Internet

https://doi.org/10.1186/s13018-022-03467-w

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