NVX-CoV2373-induced T- and B-cellular immunity in immunosuppressed people with multiple sclerosis that failed to respond to mRNA and viral vector SARS-CoV-2 vaccines

NVX-CoV2373-induced T- and B-cellular immunity in immunosuppressed people with multiple sclerosis that failed to respond to mRNA and viral vector SARS-CoV-2 vaccines

ImportanceImmunological response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is important, especially in people with multiple sclerosis (pwMS) on immunosuppressive therapies.ObjectiveThis study aims to determine whether adjuvanted protein-based vaccine NVX-CoV2373 is...

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Bibliographic Details
Main Authors: Magdalena Mueller-Enz, Christina Woopen, Georges Katoul Al Rahbani, Rocco Haase, Marie Dunsche, Tjalf Ziemssen, Katja Akgün
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2 vaccination
NVX-CoV2373
multiple sclerosis
sphingosine-1phosphate receptor modulators
anti-CD20 therapy
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1081933/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1081933/full

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