The Role of the Innate Immune System in Wear Debris-Induced Inflammatory Peri-Implant Osteolysis in Total Joint Arthroplasty

Periprosthetic osteolysis remains a leading complication of total hip and knee arthroplasty, often resulting in aseptic loosening of the implant and necessitating revision surgery. Wear-induced particulate debris is the main cause initiating this destructive process. The purpose of this article is t...

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Bibliographic Details
Main Authors: John Patrick Connors, John W. Stelzer, Patrick M. Garvin, Ian J. Wellington, Olga Solovyova
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/9/12/764