Biodistribution and toxicity assessment of methoxyphenyl phosphonium carbosilane dendrimers in 2D and 3D cell cultures of human cancer cells and zebrafish embryos
Abstract The consideration of human and environmental exposure to dendrimers, including cytotoxicity, acute toxicity, and cell and tissue accumulation, is essential due to their significant potential for various biomedical applications. This study aimed to evaluate the biodistribution and toxicity o...
Main Authors: | Zuzana Žmudová, Zuzana Šanderová, Michaela Liegertová, Stanislav Vinopal, Regina Herma, Luděk Sušický, Monika Müllerová, Tomáš Strašák, Jan Malý |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-42850-3 |
Similar Items
-
Carbosilane and Carbosiloxane Dendrimers
by: Jang Hwan Hong, et al.
Published: (2009-09-01) -
Comparative Study of Functionalized Carbosilane Dendrimers for siRNA Delivery: Synthesis, Cytotoxicity, and Biophysical Properties
by: Monika Müllerová, et al.
Published: (2024-12-01) -
Antiviral mechanism of polyanionic carbosilane dendrimers against HIV-1
by: Vacas-Córdoba E, et al.
Published: (2016-04-01) -
Synthesis and Characterization of Photo-Responsive Carbosilane Dendrimers
by: Daiyo Terunuma, et al.
Published: (2009-06-01) -
Interaction of Cationic Carbosilane Dendrimers and Their siRNA Complexes with MCF-7 Cells Cultured in 3D Spheroids
by: Kamila Białkowska, et al.
Published: (2022-05-01)