Reduction in the activity of VTA/SNc dopaminergic neurons underlies aging-related decline in novelty seeking

Abstract Curiosity, or novelty seeking, is a fundamental mechanism motivating animals to explore and exploit environments to improve survival, and is also positively associated with cognitive, intrapersonal and interpersonal well-being in humans. However, curiosity declines as humans age, and the de...

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Bibliographic Details
Main Authors: Qiang Shan, Ye Tian, Hang Chen, Xiaoli Lin, Yao Tian
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05571-x