Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals

Conserved regulatory logic at accessible and inaccessible chromatin during the acute inflammatory response in mammals

Genetic elements that control inflammatory gene expression are not fully elucidated. Here the authors conduct a multi-species analysis of chromatin landscape and NF-κB binding in response to the proinflammatory cytokine TNFα, finding that conserved NF-κB bound regions are linked to enhancer activity...

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Bibliographic Details
Main Authors: Azad Alizada, Nadiya Khyzha, Liangxi Wang, Lina Antounians, Xiaoting Chen, Melvin Khor, Minggao Liang, Kumaragurubaran Rathnakumar, Matthew T. Weirauch, Alejandra Medina-Rivera, Jason E. Fish, Michael D. Wilson
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20765-1

Internet

https://doi.org/10.1038/s41467-020-20765-1

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