Protective effect of silencing Stat1 on high glucose-induced podocytes injury via Forkhead transcription factor O1-regulated the oxidative stress response

Protective effect of silencing Stat1 on high glucose-induced podocytes injury via Forkhead transcription factor O1-regulated the oxidative stress response

Abstract Background Podocyte plays an important role in maintaining the integrity and function of the glomerular filtration barrier. Various studies reported that forkhead transcription factor (Fox) O1 played a key role in anti-oxidative signaling. This study aimed to investigate the role of Stat1 i...

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Bibliographic Details
Main Authors: Hongkun Wang, Yanhui Zhang, Fangfang Xia, Wei Zhang, Peng Chen, Guoan Yang
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Molecular and Cell Biology
Subjects:
Stat1
FoxO1
Podocyte
HG
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12860-019-0209-0

Internet

http://link.springer.com/article/10.1186/s12860-019-0209-0

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