Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants

Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants

Abstract Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection against new variants of concern (VOCs) has not been firmly established. Her...

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Bibliographic Details
Main Authors: Trung The Tran, Eline Benno Vaage, Adi Mehta, Adity Chopra, Lisa Tietze, Anette Kolderup, Aina Anthi, Marton König, Gro Nygaard, Andreas Lind, Fredrik Müller, Lise Sofie Nissen-Meyer, Per Magnus, Lill Trogstad, Siri Mjaaland, Arne Søraas, Karsten Midtvedt, Anders Åsberg, Andreas Barratt-Due, Asle W. Medhus, Marte Lie Høivk, Knut Lundin, Randi Fuglaas Karlsen, Reidun Dahle, Karin Danielsson, Kristine Stien Thomassen, Grete Birkeland Kro, Rebecca J. Cox, Fan Zhou, Nina Langeland, Pål Aukrust, Espen Melum, Tone Lise Åvitsland, Kristine Wiencke, Jan Cato Holter, Ludvig A. Munthe, Gunnveig Grødeland, Jan-Terje Andersen, John Torgils Vaage, Fridtjof Lund-Johansen
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00586-7

Internet

https://doi.org/10.1038/s41541-022-00586-7

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