Col1a1 mediates the focal adhesion pathway affecting hearing in miR-29a mouse model by RNA-seq analysis

Col1a1 mediates the focal adhesion pathway affecting hearing in miR-29a mouse model by RNA-seq analysis

Age-related hearing loss (ARHL) is a common neurodegenerative disease. Its molecular mechanisms have not been fully elucidated. In the present study, we obtained differential mRNA expression in the cochlea of 2-month-old miR-29a+/+ mice and miR-29a−/− mice by RNA-seq. Gene ontology (GO) analysis was...

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Bibliographic Details
Main Authors: Shuli Wang, Mulan Li, Pengcheng Liu, Yaning Dong, Ruishuang Geng, Tihua Zheng, Qingyin Zheng, Bo Li, Peng Ma
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Experimental Gerontology
Subjects:
Age-related hearing loss
RNA-seq
miR-29a
Col1a1
Focal adhesion pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S053155652300270X

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http://www.sciencedirect.com/science/article/pii/S053155652300270X

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