Plasmodium yoelii iron transporter PyDMT1 interacts with host ferritin and is required in full activity for malarial pathogenesis

Abstract Background The rapid reproduction of malaria parasites requires proper iron uptake. However, the process of iron absorption by parasites is rarely studied. Divalent metal transporter (DMT1) is a critical iron transporter responsible for uptaking iron. A homolog of human DMT1 exists in the m...

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Bibliographic Details
Main Authors: Mengjiao Zhong, Bing Zhou
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-023-01776-y