Age-Dependent Sex Differences in Perineuronal Nets in an <i>APP</i> Mouse Model of Alzheimer’s Disease Are Brain Region-Specific

Alzheimer’s disease (AD) is the most common form of dementia, which disproportionately affects women. AD symptoms include progressive memory loss associated with amyloid-β (Aβ) plaques and dismantled synaptic mechanisms. Perineuronal nets (PNNs) are important components of the extracellular matrix w...

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Bibliographic Details
Main Authors: Rayane Rahmani, Naiomi Rambarack, Jaijeet Singh, Andrew Constanti, Afia B. Ali
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/19/14917