Synthesis, antiproliferative and antimicrobial activities of (KLAKLAK)2-NH2 analogue containing nor-Leu and its conjugates with a second pharmacophore

Synthesis, antiproliferative and antimicrobial activities of (KLAKLAK)2-NH2 analogue containing nor-Leu and its conjugates with a second pharmacophore

Peptides are a promising alternative of conventional medical drugs for the treatment of different diseases because they have no or have very few side effects owing to the natural mechanisms for their elimination. There are a lot of examples of drugs on the pharmaceutical market based on modified ami...

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Bibliographic Details
Main Authors: Sirine Jaber, Veronica Nemska, Ivan Iliev, Elena Ivanova, Tsvetelina Foteva, Nelly Georgieva, Ivan Givechev, Dimiter Tanev, Emilia Naydenova, Dancho Danalev
Format: Article
Language:English
Published: Taylor & Francis Group 2023-03-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Antiproliferative properties
antibacterial properties
caffeic acid
(KLAKLAK)2
1,8-naphthalimide
unnatural amino acids
Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2022.2162965

Internet

https://www.tandfonline.com/doi/10.1080/13102818.2022.2162965

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