Urinary DNA as a Tool for Germline and Somatic Mutation Detection in Castration-Resistant Prostate Cancer Patients

Urinary DNA as a Tool for Germline and Somatic Mutation Detection in Castration-Resistant Prostate Cancer Patients

(1) Background: DNA damage response (DDR) pathway gene mutations are detectable in a significant number of patients with metastatic castration-resistant prostate cancer (mCRPC). The study aimed at identification of germline and/or somatic DDR mutations in blood and urine samples from patients with m...

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Bibliographic Details
Main Authors: Tomas Januskevicius, Rasa Sabaliauskaite, Daiva Dabkeviciene, Ieva Vaicekauskaite, Ilona Kulikiene, Agne Sestokaite, Asta Vidrinskaite, Arnas Bakavicius, Feliksas Jankevicius, Albertas Ulys, Sonata Jarmalaite
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
DNA damage repair
<i>BRCA1/BRCA2</i> genes
castration-resistant prostate cancer
abiraterone acetate
Online Access:https://www.mdpi.com/2227-9059/11/3/761

Internet

https://www.mdpi.com/2227-9059/11/3/761

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