The emerging roles and therapeutic potential of cyclin M/CorC family of Mg2+ transporters

Cyclin M (CNNM) and its prokaryotic ortholog CorC belong to a family of proteins that function as Mg2+-extruding transporters by stimulating Na+/Mg2+ exchange, and thereby control intracellular Mg2+ levels. The Mg2+-extruding function of CNNM is inhibited by the direct binding of an oncogenic protei...

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Bibliographic Details
Main Authors: Yosuke Funato, Hiroaki Miki
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000906