Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer

Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer

<i>TP53</i> is a tumor suppressor gene that encodes a sequence-specific DNA-binding transcription factor activated by stressful stimuli; it upregulates target genes involved in growth suppression, cell death, DNA repair, metabolism, among others. <i>TP53</i> is the most frequ...

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Bibliographic Details
Main Authors: Shengliang Zhang, Lindsey Carlsen, Liz Hernandez Borrero, Attila A. Seyhan, Xiaobing Tian, Wafik S. El-Deiry
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biomolecules
Subjects:
P53
mutant p53
targeting therapy
immunotherapy
cancer
Online Access:https://www.mdpi.com/2218-273X/12/4/548

Internet

https://www.mdpi.com/2218-273X/12/4/548

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