Factors Contributing to Drug Release From Enteric-Coated Omeprazole Capsules: An In Vitro and In Vivo Pharmacokinetic Study and IVIVC Evaluation in Beagle Dogs

This study was performed to explore factors influencing the release of the proton pump inhibitor omeprazole from enteric-coated capsules in vitro and absorption in vivo in beagle dogs. Enteric-coated pellets with different enteric coating materials and coating levels were designed and prepared. All...

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Bibliographic Details
Main Authors: Cheng Cui, Jiabei Sun, Xueqing Wang, Zhenxi Yu, Yaqin Shi
Format: Article
Language:English
Published: SAGE Publishing 2020-03-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325820908980