2-Hydroxy-<i>N</i>-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase

2-Hydroxy-<i>N</i>-phenylbenzamides and Their Esters Inhibit Acetylcholinesterase and Butyrylcholinesterase

The development of novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) represents a viable approach to alleviate Alzheimer&#8217;s disease. Thirty-six halogenated 2-hydroxy-<i>N</i>-phenylbenzamides (salicylanilides) with various substitution patterns an...

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Bibliographic Details
Main Authors: Martin Krátký, Šárka Štěpánková, Neto-Honorius Houngbedji, Rudolf Vosátka, Katarína Vorčáková, Jarmila Vinšová
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Biomolecules
Subjects:
acetylcholinesterase
benzamides
butyrylcholinesterase
enzyme inhibition
esters
in vitro inhibition
phosphorus derivatives
salicylanilides
Online Access:https://www.mdpi.com/2218-273X/9/11/698

Internet

https://www.mdpi.com/2218-273X/9/11/698

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