In vivo MRI and PET imaging in a translational ILD mouse model expressing non-resolving fibrosis and bronchiectasis-like pathology after repeated systemic exposure to bleomycin

In vivo MRI and PET imaging in a translational ILD mouse model expressing non-resolving fibrosis and bronchiectasis-like pathology after repeated systemic exposure to bleomycin

Drug-induced interstitial lung disease (ILD) is crucial to detect early to achieve the best treatment outcome. Optimally, non-invasive imaging biomarkers can be used for early detection of disease progression and treatment follow-up. Therefore, reliable in vivo models are warranted in new imaging bi...

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Bibliographic Details
Main Authors: Irma Mahmutovic Persson, Nina Fransén Petterson, Jian Liu, René in ‘t Zandt, Carla Carvalho, Anders Örbom, Lars E. Olsson, Karin von Wachenfeldt
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Medicine
Subjects:
longitudinal imaging
chronic model
lung toxicity/lung injury
drug-induced interstitial lung disease
fibrosis
animal models/mouse models
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1276420/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2024.1276420/full

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